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SU 4942

Name: SU 4942
Brand: TargetMol
SKU: T3567
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3567Cas No. 76086-99-2

SU-4942 is a regulator of tyrosine kinase signaling. It inhibits VEGF and endothelial cell growth factor (ECGF)-induced mitosis in endothelial cells (US5792783A).

SU 4942

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Purity: 99.32%

Catalog No. T3567Cas No. 76086-99-2

SU-4942 is a regulator of tyrosine kinase signaling. It inhibits VEGF and endothelial cell growth factor (ECGF)-induced mitosis in endothelial cells (US5792783A).

Pack Size	Price	Availability
25 mg	$40	In Stock
50 mg	$61	In Stock
100 mg	$92	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.32%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

SU-4942 is a regulator of tyrosine kinase signaling. It inhibits VEGF and endothelial cell growth factor (ECGF)-induced mitosis in endothelial cells (US5792783A).

Chemical Properties

Molecular Weight	300.15
Formula	C₁₅H₁₀BrNO
Cas No.	76086-99-2
Smiles	Brc1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
Relative Density.	1.539 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (149.93 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3317 mL	16.6583 mL	33.3167 mL	166.5834 mL
5 mM	0.6663 mL	3.3317 mL	6.6633 mL	33.3167 mL
10 mM	0.3332 mL	1.6658 mL	3.3317 mL	16.6583 mL
20 mM	0.1666 mL	0.8329 mL	1.6658 mL	8.3292 mL
50 mM	0.0666 mL	0.3332 mL	0.6663 mL	3.3317 mL
100 mM	0.0333 mL	0.1666 mL	0.3332 mL	1.6658 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc