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Tetrahydroharmine

Name: Tetrahydroharmine
Brand: TargetMol
SKU: TN7211
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN7211Cas No. 17019-01-1

Alias Leptaflorine

Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A inhibitor.

Tetrahydroharmine

🥰Excellent

Purity: 99.98%

Catalog No. TN7211Alias LeptaflorineCas No. 17019-01-1

Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A inhibitor.

Pack Size	Price	Availability
5 mg	$50	In Stock
10 mg	$75	In Stock
25 mg	$128	In Stock
50 mg	$192	In Stock
100 mg	$287	In Stock
1 mL x 10 mM (in DMSO)	$58	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.98%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A inhibitor.
Targets&IC50	MAO-B:74 nM
Synonyms	Leptaflorine

Chemical Properties

Molecular Weight	216.28
Formula	C₁₃H₁₆N₂O
Cas No.	17019-01-1
Smiles	COC1=CC=C2C(NC3=C2CCNC3C)=C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (254.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6236 mL	23.1182 mL	46.2364 mL	231.1818 mL
5 mM	0.9247 mL	4.6236 mL	9.2473 mL	46.2364 mL
10 mM	0.4624 mL	2.3118 mL	4.6236 mL	23.1182 mL
20 mM	0.2312 mL	1.1559 mL	2.3118 mL	11.5591 mL
50 mM	0.0925 mL	0.4624 mL	0.9247 mL	4.6236 mL
100 mM	0.0462 mL	0.2312 mL	0.4624 mL	2.3118 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc