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Carboxylesterase-IN-2

Name: Carboxylesterase-IN-2
Brand: TargetMol
SKU: T77524
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T77524Cas No. 2764748-88-9

Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.

Carboxylesterase-IN-2

🥰Excellent

Purity: 99.92%

Catalog No. T77524Cas No. 2764748-88-9

Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.

Pack Size	Price	Availability
1 mg	$56	In Stock
5 mg	$143	In Stock
10 mg	$227	In Stock
25 mg	$389	In Stock
50 mg	$535	In Stock
100 mg	$738	In Stock
200 mg	$993	In Stock
1 mL x 10 mM (in DMSO)	$158	In Stock

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Batch Information

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Purity:99.92%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.
Targets&IC50	Carboxyl esterase Notum:＜10 nM

Chemical Properties

Molecular Weight	272.33
Formula	C₁₃H₁₂N₄OS
Cas No.	2764748-88-9
Smiles	O=C1N2C(C=CC(SC3=CC(C)=C(C)C=C3)=N2)=NN1
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 70 mg/mL (257.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6720 mL	18.3601 mL	36.7202 mL	183.6008 mL
5 mM	0.7344 mL	3.6720 mL	7.3440 mL	36.7202 mL
10 mM	0.3672 mL	1.8360 mL	3.6720 mL	18.3601 mL
20 mM	0.1836 mL	0.9180 mL	1.8360 mL	9.1800 mL
50 mM	0.0734 mL	0.3672 mL	0.7344 mL	3.6720 mL
100 mM	0.0367 mL	0.1836 mL	0.3672 mL	1.8360 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc