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Boc-NH-C12-NH2
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Catalog No. T17652Cas No. 109792-60-1
Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker suitable for use in PROTAC synthesis.
Boc-NH-C12-NH2
🥰Excellent
Catalog No. T17652Cas No. 109792-60-1
Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker suitable for use in PROTAC synthesis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $29 | In Stock |
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Purity:≥98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker suitable for use in PROTAC synthesis. |
| In vitro | PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase and the other targets the desired protein. They utilize the ubiquitin-proteasome system to selectively degrade specific proteins[1]. |
| Molecular Weight | 300.48 |
| Formula | C17H36N2O2 |
| Cas No. | 109792-60-1 |
| Smiles | N(CCCCCCCCCCCCN)C(OC(C)(C)C)=O |
| Relative Density. | 0.924g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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