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FT113

Name: FT113
Brand: TargetMol
SKU: T7947
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7947Cas No. 1630808-89-7

FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity

FT113

🥰Excellent

Purity: 97.05%

Catalog No. T7947Cas No. 1630808-89-7

FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity

Pack Size	Price	Availability
5 mg	$31	In Stock
10 mg	$53	In Stock
25 mg	$119	In Stock
50 mg	$209	In Stock
100 mg	$358	In Stock
200 mg	$497	In Stock
1 mL x 10 mM (in DMSO)	$35	In Stock

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Batch Information

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Purity:97.05%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
Targets&IC50	Fas:213 nM
In vivo	FT113, a compound with potent biochemical and cellular activity, which translated into excellent activity in in vivo models.Caused 32 % and 50% tumor growth inhibition at 25 and 50 mg/kg, respectively in mice.
Animal Research	Athymic nude mice bearing MV-411 cells. Dosage:5, 25, or 50 mg/kg, twice daily for 16 days

Chemical Properties

Molecular Weight	409.41
Formula	C₂₂H₂₀FN₃O₄
Cas No.	1630808-89-7
Smiles	OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1
Relative Density.	1.456 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 62.5 mg/mL (152.66 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4425 mL	12.2127 mL	24.4254 mL	122.1270 mL
5 mM	0.4885 mL	2.4425 mL	4.8851 mL	24.4254 mL
10 mM	0.2443 mL	1.2213 mL	2.4425 mL	12.2127 mL
20 mM	0.1221 mL	0.6106 mL	1.2213 mL	6.1063 mL
50 mM	0.0489 mL	0.2443 mL	0.4885 mL	2.4425 mL
100 mM	0.0244 mL	0.1221 mL	0.2443 mL	1.2213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc