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6-OAU

🥰Excellent
Catalog No. T2036Cas No. 83797-69-7
Alias GTPL5846

6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.

6-OAU

6-OAU

🥰Excellent
Purity: 99.01%
Catalog No. T2036Alias GTPL5846Cas No. 83797-69-7
6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$163In StockIn Stock
2 mg$226In StockIn Stock
5 mg$347In StockIn Stock
10 mg$497In StockIn Stock
25 mg$793In StockIn Stock
50 mg$1,130In StockIn Stock
100 mg$1,520-In Stock
1 mL x 10 mM (in DMSO)$317In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.01%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.
Targets&IC50
GPR84:105 nM (EC50)
SynonymsGTPL5846
Chemical Properties
Molecular Weight239.31
FormulaC12H21N3O2
Cas No.83797-69-7
SmilesCCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (229.83 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1787 mL20.8934 mL41.7868 mL208.9340 mL
5 mM0.8357 mL4.1787 mL8.3574 mL41.7868 mL
10 mM0.4179 mL2.0893 mL4.1787 mL20.8934 mL
20 mM0.2089 mL1.0447 mL2.0893 mL10.4467 mL
50 mM0.0836 mL0.4179 mL0.8357 mL4.1787 mL
100 mM0.0418 mL0.2089 mL0.4179 mL2.0893 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

U937TNF-αSf9rat air pouch modelproinflammatory cytokinePMNMAPKsmacrophageLauric acidInhibitorinhibitinflammationIL-8HEK293GTPγSGTPL-5846GTPL 5846GPR84G protein-coupled receptorG protein coupled receptor 84Extracellular signal regulated kinasesERKCytokineschemotaxisB. abortus6-OAU6OAU6 OAU
Related Tags: buy 6-OAU | purchase 6-OAU | 6-OAU cost | order 6-OAU | 6-OAU chemical structure | 6-OAU formula | 6-OAU molecular weight
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