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Dimethyl sulfoxide
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Catalog No. T0341Cas No. 67-68-5
Alias DMSO
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
Dimethyl sulfoxide
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Catalog No. T0341Alias DMSOCas No. 67-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 mL | $43 | In Stock | - | |
| 500 mL | $78 | In Stock | In Stock |
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Storage & Solubility Information
| Description | Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity. |
| Targets&IC50 | Smooth muscle cells (SMCs):0.01, SOD1 (endothelial cells):0.029 |
| In vitro | METHODS: Human colorectal cancer cells HCT-116 and SW-480 were treated with Dimethyl sulfoxide (0.1%-1.5%) for 24 h, and cell viability was measured by MTT. RESULTS: Dimethyl sulfoxide showed a dose-dependent effect on cell proliferation. Cells treated with 1.5% Dimethyl sulfoxide showed about 10% reduction in cell growth. [1] |
| In vivo | METHODS: To detect toxicity, Dimethyl sulfoxide (10%-100%) was administered to Swiss mice by single intraperitoneal injection for five days. RESULTS: The LD50 increased with decreasing concentration and the LD50 values for 10%, 25%, 50%, 75%, and 100% Dimethyl sulfoxide were >10.1, 15.4, 13.3, 11.9, and 10.9 g/kg, respectively. [2] |
| Synonyms | DMSO |
| Molecular Weight | 78.13 |
| Formula | C2H6OS |
| Cas No. | 67-68-5 |
| Smiles | O=S(C)C |
| Relative Density. | 1.1 g/cm3. Temperature:20 °C.;1.09 g/cm3. Temperature:30 °C.;1.08 g/cm3. Temperature:40 °C. |
| Storage | store at RT |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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