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Dimethyl sulfoxide
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Catalog No. T0341Cas No. 67-68-5
Alias DMSO
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
Dimethyl sulfoxide
🥰Excellent
Catalog No. T0341Alias DMSOCas No. 67-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 mL | $43 | In Stock | |
| 500 mL | $78 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity. |
| Targets&IC50 | Smooth muscle cells (SMCs):0.01, SOD1 (endothelial cells):0.029 |
| In vitro | METHODS: Human colorectal cancer cells HCT-116 and SW-480 were treated with Dimethyl sulfoxide (0.1%-1.5%) for 24 h, and cell viability was measured by MTT. RESULTS: Dimethyl sulfoxide showed a dose-dependent effect on cell proliferation. Cells treated with 1.5% Dimethyl sulfoxide showed about 10% reduction in cell growth. [1] |
| In vivo | METHODS: To detect toxicity, Dimethyl sulfoxide (10%-100%) was administered to Swiss mice by single intraperitoneal injection for five days. RESULTS: The LD50 increased with decreasing concentration and the LD50 values for 10%, 25%, 50%, 75%, and 100% Dimethyl sulfoxide were >10.1, 15.4, 13.3, 11.9, and 10.9 g/kg, respectively. [2] |
| Synonyms | DMSO |
| Molecular Weight | 78.133 |
| Formula | C2H6OS |
| Cas No. | 67-68-5 |
| Smiles | O=S(C)C |
| Relative Density. | 1.1 g/cm3. Temperature:20 °C.;1.09 g/cm3. Temperature:30 °C.;1.08 g/cm3. Temperature:40 °C. |
Storage & Solubility Information
| Storage | -20°C for 2 years, 4°C for 1 year |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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