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Amifostine

Name: Amifostine
Brand: TargetMol
SKU: T3289
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3289Cas No. 20537-88-6

Alias WR2721, Gammaphos, Ethyol

Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.

Amifostine

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Purity: 99.88%

Catalog No. T3289Alias WR2721, Gammaphos, EthyolCas No. 20537-88-6

Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$44	In Stock
25 mg	$94	In Stock
50 mg	$132	In Stock
100 mg	$186	In Stock
200 mg	$259	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.
Synonyms	WR2721, Gammaphos, Ethyol

Chemical Properties

Molecular Weight	214.22
Formula	C₅H₁₅N₂O₃PS
Cas No.	20537-88-6
Smiles	NCCCNCCSP(O)(O)=O
Relative Density.	1.367 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40 mg/mL (186.72 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	4.6681 mL	23.3405 mL	46.6810 mL	233.4049 mL
5 mM	0.9336 mL	4.6681 mL	9.3362 mL	46.6810 mL
10 mM	0.4668 mL	2.3340 mL	4.6681 mL	23.3405 mL
20 mM	0.2334 mL	1.1670 mL	2.3340 mL	11.6702 mL
50 mM	0.0934 mL	0.4668 mL	0.9336 mL	4.6681 mL
100 mM	0.0467 mL	0.2334 mL	0.4668 mL	2.3340 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc