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Amifostine

🥰Excellent
Catalog No. T3289Cas No. 20537-88-6
Alias WR2721, Gammaphos, Ethyol

Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.

Amifostine
Other Forms of Amifostine:

Amifostine

🥰Excellent
Purity: 99.88%
Catalog No. T3289Alias WR2721, Gammaphos, EthyolCas No. 20537-88-6
Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$44In StockIn Stock
25 mg$89In StockIn Stock
50 mg$126In StockIn Stock
100 mg$176In Stock-
200 mg$247In Stock-
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.88%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.
SynonymsWR2721, Gammaphos, Ethyol
Chemical Properties
Molecular Weight214.22
FormulaC5H15N2O3PS
Cas No.20537-88-6
SmilesNCCCNCCSP(O)(O)=O
Relative Density.1.367 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 40 mg/mL (186.72 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM4.6681 mL23.3405 mL46.6810 mL233.4049 mL
5 mM0.9336 mL4.6681 mL9.3362 mL46.6810 mL
10 mM0.4668 mL2.3340 mL4.6681 mL23.3405 mL
20 mM0.2334 mL1.1670 mL2.3340 mL11.6702 mL
50 mM0.0934 mL0.4668 mL0.9336 mL4.6681 mL
100 mM0.0467 mL0.2334 mL0.4668 mL2.3340 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

WR-2721WR 2721thiolradioprotectorp53MDM-2/p53InhibitorinhibitHypoxia-inducible factorsHIF-α1HIFsHIFProlylHydroxylaseHIF-PHHIF/HIFProlylHydroxylaseHIF/HIF Prolyl-HydroxylaseHIF/HIF ProlylHydroxylaseHIF Prolyl-HydroxylaseHIF ProlylHydroxylaseHIFDNA-damagecytoprotectiveBroad-spectrumantiangiogenicAmifostine
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