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Iohexol

Name: Iohexol
Brand: TargetMol
SKU: T1554
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1554Cas No. 66108-95-0

Iohexol is an X-ray contrast agent containing varying concentrations of iohexol, which can be used for a variety of imaging applications.

Iohexol

🥰Excellent

Purity: 99.89%

Catalog No. T1554Cas No. 66108-95-0

Iohexol is an X-ray contrast agent containing varying concentrations of iohexol, which can be used for a variety of imaging applications.

Pack Size	Price	Availability
100 mg	$41	In Stock
500 mg	$68	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.89%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Iohexol is an X-ray contrast agent containing varying concentrations of iohexol, which can be used for a variety of imaging applications.

Kinase Assay

H1-Antihistaminic Activity: The segments (1 cm) of isolated ileum from guinea pigs are suspended in an organ bath containing Tyrode solution (ventilation, 32 °C). The contractile responses to histamine (0.54 μM) are measured with an isotonic transducer. A set concentration of Chlorpheniramine is added in the organ bath 5 minutes before the addition of histamine. IC50 value of Chlorpheniramine is calculated by the probit methond.

Chemical Properties

Molecular Weight	821.14
Formula	C₁₉H₂₆I₃N₃O₉
Cas No.	66108-95-0
Smiles	N(CC(CO)O)(C(C)=O)C1=C(I)C(C(NCC(CO)O)=O)=C(I)C(C(NCC(CO)O)=O)=C1I
Relative Density.	2.2 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40 mg/mL (48.71 mM), Sonication is recommended.

DMSO: 50 mg/mL (60.89 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.44 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2178 mL	6.0891 mL	12.1782 mL	60.8910 mL
5 mM	0.2436 mL	1.2178 mL	2.4356 mL	12.1782 mL
10 mM	0.1218 mL	0.6089 mL	1.2178 mL	6.0891 mL
20 mM	0.0609 mL	0.3045 mL	0.6089 mL	3.0445 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0244 mL	0.1218 mL	0.2436 mL	1.2178 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc