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Resolvin D2
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Catalog No. T12707Cas No. 810668-37-2
Alias Rv-D2, RvD2
Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
Resolvin D2
Copy Product Info😃Good
Catalog No. T12707Alias Rv-D2, RvD2Cas No. 810668-37-2
Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 μg | $999 | - | In Stock | |
| 100 μg | $4,099 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Liquid
Color:Transparent
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| Description | Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer. |
| Targets&IC50 | TRPA1:2 nM, TRPV1:0.1 nM |
| In vitro | Resolvin D2 is a potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons. It may be ideal for the treatment of periapical lesions by promoting positive regression of inflammation and regeneration of pulp-like tissue following root canal infection. Resolvin D2 also reduces leukocyte-endothelial cell interactions in vivo through endothelium-dependent nitric oxide production and direct modulation of leukocyte adhesion receptor expression. [1][2] |
| In vivo | Peripheral injection of Resolvin D2 (10 ng; plantar injection) has potent inhibitory effects on inflammatory pain. [3] |
| Synonyms | Rv-D2, RvD2 |
| Molecular Weight | 376.49 |
| Formula | C22H32O5 |
| Cas No. | 810668-37-2 |
| Smiles | [C@H]([C@H](C/C=C\CC)O)(/C=C/C=C/C=C\C=C\[C@H](C/C=C\CCC(O)=O)O)O |
| Relative Density. | 1.101 g/cm3 (Predicted) |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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