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Resolvin D2
🥰Excellent
Catalog No. T12707Cas No. 810668-37-2
Alias Rv-D2, RvD2
Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
Resolvin D2
🥰Excellent
Catalog No. T12707Alias Rv-D2, RvD2Cas No. 810668-37-2
Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 μg | $999 | - | In Stock | |
| 100 μg | $4,099 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer. |
| Targets&IC50 | TRPV1:0.1 nM, TRPA1:2 nM |
| In vitro | Resolvin D2 is a potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons. It may be ideal for the treatment of periapical lesions by promoting positive regression of inflammation and regeneration of pulp-like tissue following root canal infection. Resolvin D2 also reduces leukocyte-endothelial cell interactions in vivo through endothelium-dependent nitric oxide production and direct modulation of leukocyte adhesion receptor expression. [1][2] |
| In vivo | Peripheral injection of Resolvin D2 (10 ng; plantar injection) has potent inhibitory effects on inflammatory pain. [3] |
| Synonyms | Rv-D2, RvD2 |
| Molecular Weight | 376.49 |
| Formula | C22H32O5 |
| Cas No. | 810668-37-2 |
| Smiles | [C@H]([C@H](C/C=C\CC)O)(/C=C/C=C/C=C\C=C\[C@H](C/C=C\CCC(O)=O)O)O |
| Relative Density. | 1.101 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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