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Nazartinib S-enantiomer

Name: Nazartinib S-enantiomer
Brand: TargetMol
SKU: T11156
Rating: 4.5 (1 reviews)

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Catalog No. T11156Cas No. 1508256-20-9

Alias EGF816 (S-enantiomer)

Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.

Nazartinib S-enantiomer

😃Good

Catalog No. T11156Alias EGF816 (S-enantiomer)Cas No. 1508256-20-9

Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.

Pack Size	Price	Availability
25 mg	$1,630	8-10 weeks
50 mg	$2,210	8-10 weeks
100 mg	$2,730	8-10 weeks

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Product Introduction

Bioactivity

Description	Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
Synonyms	EGF816 (S-enantiomer)

Chemical Properties

Molecular Weight	495.02
Formula	C₂₆H₃₁ClN₆O₂
Cas No.	1508256-20-9
Relative Density.	1.28 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (101.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0201 mL	10.1006 mL	20.2012 mL	101.0060 mL
5 mM	0.4040 mL	2.0201 mL	4.0402 mL	20.2012 mL
10 mM	0.2020 mL	1.0101 mL	2.0201 mL	10.1006 mL
20 mM	0.1010 mL	0.5050 mL	1.0101 mL	5.0503 mL
50 mM	0.0404 mL	0.2020 mL	0.4040 mL	2.0201 mL
100 mM	0.0202 mL	0.1010 mL	0.2020 mL	1.0101 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc