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Raf inhibitor 2

🥰Excellent
Catalog No. T4194Cas No. 220904-99-4
Alias CID-25014542, CID25014542, CID 25014542

Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.

Raf inhibitor 2

Raf inhibitor 2

🥰Excellent
Purity: 98.53%
Catalog No. T4194Alias CID-25014542, CID25014542, CID 25014542Cas No. 220904-99-4
Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$39In StockIn Stock
10 mg$62In StockIn Stock
25 mg$117In StockIn Stock
50 mg$177In StockIn Stock
100 mg$258In StockIn Stock
200 mg$362In StockIn Stock
1 mL x 10 mM (in DMSO)$41In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.53%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.
SynonymsCID-25014542, CID25014542, CID 25014542
Chemical Properties
Molecular Weight429.49
FormulaC15H8Br2ClNO2
Cas No.220904-99-4
SmilesOc1c(Br)cc(\C=C2/C(=O)Nc3ccc(Cl)cc23)cc1Br
Relative Density.1.938 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (69.85 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3283 mL11.6417 mL23.2834 mL116.4171 mL
5 mM0.4657 mL2.3283 mL4.6567 mL23.2834 mL
10 mM0.2328 mL1.1642 mL2.3283 mL11.6417 mL
20 mM0.1164 mL0.5821 mL1.1642 mL5.8209 mL
50 mM0.0466 mL0.2328 mL0.4657 mL2.3283 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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