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Cimicoxib

Name: Cimicoxib
Brand: TargetMol
SKU: T30937
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T30937Cas No. 265114-23-6

Alias UR-8880, UR8880, trade name: Cimalgex

Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.

Cimicoxib

🥰Excellent

Purity: 98.22%

Catalog No. T30937Alias UR-8880, UR8880, trade name: CimalgexCas No. 265114-23-6

Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.

Pack Size	Price	Availability
1 mg	$39	In Stock
2 mg	$53	In Stock
5 mg	$76	In Stock
10 mg	$113	In Stock
25 mg	$188	In Stock
50 mg	$283	In Stock
100 mg	$422	In Stock
1 mL x 10 mM (in DMSO)	$93	In Stock

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Batch Information

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Purity:98.22%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.
Synonyms	UR-8880, UR8880, trade name: Cimalgex

Chemical Properties

Molecular Weight	381.81
Formula	C₁₆H₁₃ClFN₃O₃S
Cas No.	265114-23-6
Smiles	ClC1=C(N(C=N1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC(F)=C(OC)C=C3
Relative Density.	1.49 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (130.96 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6191 mL	13.0955 mL	26.1910 mL	130.9552 mL
5 mM	0.5238 mL	2.6191 mL	5.2382 mL	26.1910 mL
10 mM	0.2619 mL	1.3096 mL	2.6191 mL	13.0955 mL
20 mM	0.1310 mL	0.6548 mL	1.3096 mL	6.5478 mL
50 mM	0.0524 mL	0.2619 mL	0.5238 mL	2.6191 mL
100 mM	0.0262 mL	0.1310 mL	0.2619 mL	1.3096 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc