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Ralaniten triacetate

Name: Ralaniten triacetate
Brand: TargetMol
SKU: T36375
Price: 165 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T36375Cas No. 1637573-04-6

Alias EPI-506

Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate and breast cancer.

Ralaniten triacetate

🥰Excellent

Purity: 98.69%

Catalog No. T36375Alias EPI-506Cas No. 1637573-04-6

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$165	-	In Stock
5 mg	$413	-	In Stock
10 mg	$689	-	In Stock
25 mg	$1,490	-	In Stock
50 mg	$1,980	-	In Stock
100 mg	$2,500	-	In Stock
1 mL x 10 mM (in DMSO)	$473	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:98.69%

ee:97.98%

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Product Introduction

Bioactivity

Description	Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate and breast cancer.
In vitro	Ralaniten triacetate (EPI-506) is a highly specific small molecule targeting the N-terminal domain (NTD) of the androgen receptor (AR). It is commonly used in research on metastatic castration-resistant prostate cancer (mCRPC), where resistance to androgen deprivation therapy has developed[2].
Synonyms	EPI-506

Chemical Properties

Molecular Weight	521.00
Formula	C₂₇H₃₃ClO₈
Cas No.	1637573-04-6
Smiles	CC(=O)OC[C@H](COc1ccc(cc1)C(C)(C)c1ccc(OC[C@@H](CCl)OC(C)=O)cc1)OC(C)=O
Relative Density.	1.188 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (153.55 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (6.33 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9194 mL	9.5969 mL	19.1939 mL	95.9693 mL
5 mM	0.3839 mL	1.9194 mL	3.8388 mL	19.1939 mL
10 mM	0.1919 mL	0.9597 mL	1.9194 mL	9.5969 mL
20 mM	0.0960 mL	0.4798 mL	0.9597 mL	4.7985 mL
50 mM	0.0384 mL	0.1919 mL	0.3839 mL	1.9194 mL
100 mM	0.0192 mL	0.0960 mL	0.1919 mL	0.9597 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc