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HMN-154

Name: HMN-154
Brand: TargetMol
SKU: T4025
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4025Cas No. 173528-92-2

Alias HMN154

HMN-154, a novel benzenesulfonamide anticancer compound, interacts with NF-YB and disrupts the binding of the NF-Y heterotrimer to DNA.

HMN-154

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Purity: 98.25%

Catalog No. T4025Alias HMN154Cas No. 173528-92-2

HMN-154, a novel benzenesulfonamide anticancer compound, interacts with NF-YB and disrupts the binding of the NF-Y heterotrimer to DNA.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$41	In Stock	In Stock
5 mg	$113	In Stock	In Stock
10 mg	$172	In Stock	In Stock
25 mg	$223	In Stock	In Stock
50 mg	$273	In Stock	In Stock
100 mg	$323	In Stock	In Stock
200 mg	$456	-	In Stock
1 mL x 10 mM (in DMSO)	$92	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.25%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	HMN-154, a novel benzenesulfonamide anticancer compound, interacts with NF-YB and disrupts the binding of the NF-Y heterotrimer to DNA.
Targets&IC50	Colon38 cells:0.003 μg/mL, KB:0.0026 μg/mL
Synonyms	HMN154

Chemical Properties

Molecular Weight	366.43
Formula	C₂₀H₁₈N₂O₃S
Cas No.	173528-92-2
Smiles	COc1ccc(cc1)S(=O)(=O)Nc1ccccc1\C=C\c1ccncc1
Relative Density.	1.313g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 15 mg/mL (40.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7290 mL	13.6452 mL	27.2903 mL	136.4517 mL
5 mM	0.5458 mL	2.7290 mL	5.4581 mL	27.2903 mL
10 mM	0.2729 mL	1.3645 mL	2.7290 mL	13.6452 mL
20 mM	0.1365 mL	0.6823 mL	1.3645 mL	6.8226 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

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