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D-Menthol

Name: D-Menthol
Brand: TargetMol
SKU: TN1544
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1544Cas No. 15356-60-2

Alias Menthol, (+)-MENTHOL

D-Menthol ((+)-MENTHOL) is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α±7-nACh receptors in a noncompetitive manner.

D-Menthol

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Purity: 99.97%

Catalog No. TN1544Alias Menthol, (+)-MENTHOLCas No. 15356-60-2

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$39	-	In Stock
1 g	Inquiry	-	In Stock
5 g	Inquiry	-	In Stock
10 g	Inquiry	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White

Resource Download

COA HNMR GC

Product Introduction

Bioactivity

Description	D-Menthol ((+)-MENTHOL) is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α±7-nACh receptors in a noncompetitive manner.
In vitro	The algal biomass and the intracellular and extracellular MCY concentrations were evaluated during 5d incubation. After the D-Menthol exposure, the dry weight of the cells gradually decreased; the decrease in the dry weight after 5d exposure was 29, 12, and 2mgL(-1) when the initial cell densities were 1.4x10(7), 1.2x10(6), and 2.9x10(5)cellmL(-1), respectively. The results indicate that the D-Menthol exposure inhibited the cellular growth, thus also inhibiting the increase of the total MCY concentration. In the presence of D-Menthol, the intracellular MCY was gradually released into the medium after the cell lysis.
Synonyms	Menthol, (+)-MENTHOL

Chemical Properties

Molecular Weight	156.27
Formula	C₁₀H₂₀O
Cas No.	15356-60-2
Smiles	CC(C)[C@H]1CC[C@H](C)C[C@@H]1O
Relative Density.	0.49 g/cm3. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 257.5 mg/mL (1647.79 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.8 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.3992 mL	31.9959 mL	63.9918 mL	319.9590 mL
5 mM	1.2798 mL	6.3992 mL	12.7984 mL	63.9918 mL
10 mM	0.6399 mL	3.1996 mL	6.3992 mL	31.9959 mL
20 mM	0.3200 mL	1.5998 mL	3.1996 mL	15.9980 mL
50 mM	0.1280 mL	0.6399 mL	1.2798 mL	6.3992 mL
100 mM	0.0640 mL	0.3200 mL	0.6399 mL	3.1996 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc