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S-(4-Hydroxybenzyl)glutathione

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Catalog No. TN7044Cas No. 129636-38-0

S-(4-Hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.

S-(4-Hydroxybenzyl)glutathione

S-(4-Hydroxybenzyl)glutathione

🥰Excellent
Purity: 99.78%
Catalog No. TN7044Cas No. 129636-38-0
S-(4-Hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$64In StockIn Stock
5 mg$156In StockIn Stock
10 mg$228In Stock-
25 mg$389In Stock-
1 mL x 10 mM (in DMSO)$179In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.78%
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COA MS HPLC

Product Introduction

Bioactivity
Description
S-(4-Hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
Targets&IC50
Glutamate receptor:2 μM
In vitro
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] inhibits specific [3H]kainic acid binding to brain glutamate receptors with IC50 of 2 μM[1]. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
Chemical Properties
Molecular Weight413.45
FormulaC17H23N3O7S
Cas No.129636-38-0
SmilesN[C@@H](CCC(=O)N[C@@H](CSCc1ccc(O)cc1)C(=O)NCC(O)=O)C(O)=O
Relative Density.1.431 g/cm3 (Predicted)
SequenceγGlu-Cys(Bn(4-OH))-Gly
Sequence ShortECG
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (133.03 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4187 mL12.0934 mL24.1867 mL120.9336 mL
5 mM0.4837 mL2.4187 mL4.8373 mL24.1867 mL
10 mM0.2419 mL1.2093 mL2.4187 mL12.0934 mL
20 mM0.1209 mL0.6047 mL1.2093 mL6.0467 mL
50 mM0.0484 mL0.2419 mL0.4837 mL2.4187 mL
100 mM0.0242 mL0.1209 mL0.2419 mL1.2093 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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Keywords

S-(4-Hydroxybenzyl)glutathioneS(4Hydroxybenzyl)glutathioneS (4 Hydroxybenzyl)glutathionekainicInhibitorinhibitglutathioneGlutamate receptorglutamatebrainacid
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