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Djenkolic Acid
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Catalog No. T22311Cas No. 498-59-9
Alias S,S'-Methylenebiscysteine, jengkolic acid, Djenkolate
Djenkolic Acid (S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans(Archidendron pauciflorum), which is native to Southeast Asia. It is an uncommon but important cause of acute kidney injury in human.
Djenkolic Acid
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Purity: 98.77%
Catalog No. T22311Alias S,S'-Methylenebiscysteine, jengkolic acid, DjenkolateCas No. 498-59-9
Djenkolic Acid (S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans(Archidendron pauciflorum), which is native to Southeast Asia. It is an uncommon but important cause of acute kidney injury in human.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $30 | In Stock | In Stock | |
| 25 mg | $48 | In Stock | In Stock | |
| 50 mg | $77 | In Stock | In Stock | |
| 100 mg | $118 | In Stock | In Stock | |
| 200 mg | $175 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:98.77%
Appearance:solid
Color:White
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Product Introduction
Djenkolic Acid AI Summary
Djenkolic Acid exhibits strong growth inhibition activity against a wide range of human tumor cell lines, as evidenced by the NCI human tumor cell line growth inhibition assay. It shows significant potency in inhibiting the growth of various cancer cell lines, including renal, non-small cell lung, leukemia, ovarian, melanoma, central nervous system, colon, breast, and small cell lung cancer cell lines. The compound has demonstrated GI50 values ranging from 36,545.11 nM to 224,905.46 nM, indicating varying levels of effectiveness across different cell lines. In addition to its anti-cancer properties, Djenkolic Acid significantly inhibits sodium fluorescein uptake in OATP1B1 and OATP1B3-transfected CHO cells at a concentration of 10 μM, with inhibition levels of 92.41% and 96.92%, respectively. These findings suggest that Djenkolic Acid exhibits promising bioactivity as a potential anti-cancer agent and may also strongly interact with specific transporters..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Djenkolic Acid (S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans(Archidendron pauciflorum), which is native to Southeast Asia. It is an uncommon but important cause of acute kidney injury in human. |
| Synonyms | S,S'-Methylenebiscysteine, jengkolic acid, Djenkolate |
| Molecular Weight | 254.33 |
| Formula | C7H14N2O4S2 |
| Cas No. | 498-59-9 |
| Smiles | N[C@@H](CSCSC[C@H](N)C(O)=O)C(O)=O |
| Relative Density. | 1.4799 g/cm3 (Estimated) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 5%TFA: 3 mg/mL (11.8 mM), Sonication is recommended. DMSO: 0.1 mg/mL (0.39 mM), Sonication is recommended. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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