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AKT-IN-8

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Catalog No. T62842Cas No. 2654026-13-6

AKT-IN-8 is a potent inhibitor of AKT, demonstrating inhibitory concentrations (IC50) of 4.46 nM for AKT1, 2.44 nM for AKT2, and 9.47 nM for AKT3.

AKT-IN-8

AKT-IN-8

😃Good
Catalog No. T62842Cas No. 2654026-13-6
AKT-IN-8 is a potent inhibitor of AKT, demonstrating inhibitory concentrations (IC50) of 4.46 nM for AKT1, 2.44 nM for AKT2, and 9.47 nM for AKT3.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$2,1406-8 weeks6-8 weeks
50 mg$2,7856-8 weeks6-8 weeks
100 mg$3,5206-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
AKT-IN-8 is a potent inhibitor of AKT, demonstrating inhibitory concentrations (IC50) of 4.46 nM for AKT1, 2.44 nM for AKT2, and 9.47 nM for AKT3.
Targets&IC50
Akt3:9.47 nM, Akt1:4.46 nM, Akt2:2.44 nM
Chemical Properties
Molecular Weight456.93
FormulaC22H25ClN6O3
Cas No.2654026-13-6
SmilesC(N[C@@H](CCO)C1=CC=C(Cl)C=C1)(=O)[C@]2(N)C[C@@]3(N(C4=C5C(OC3)=CN=C5N=CN4)CC2)[H]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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