Powder: -20°C for 3 years | In solvent: -80°C for 1 year
M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 518.00 | |
5 mg | In stock | $ 1,170.00 | |
25 mg | In stock | $ 1,920.00 | |
50 mg | In stock | $ 2,380.00 | |
100 mg | In stock | $ 3,100.00 |
Description | M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells. |
Molecular Weight | 428.42 |
Formula | C23H17FN6O2 |
CAS No. | 1360628-91-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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M3541 1360628-91-6 Apoptosis DNA Damage/DNA Repair PI3K/Akt/mTOR signaling ATM/ATR M 3541 M-3541 BI-665915 BI 665915 inhibitor inhibit