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Sergliflozin etabonate

Name: Sergliflozin etabonate
Brand: TargetMol
SKU: T28757
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T28757Cas No. 408504-26-7

Alias GW-869682X, GW869682X, GW 869682X

Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.

Sergliflozin etabonate

🥰Excellent

Purity: 97.88%

Catalog No. T28757Alias GW-869682X, GW869682X, GW 869682XCas No. 408504-26-7

Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.

Pack Size	Price	Availability
1 mg	$195	In Stock
2 mg	$293	In Stock
5 mg	$448	In Stock
10 mg	$658	In Stock
25 mg	$987	In Stock
50 mg	$1,380	In Stock
100 mg	$1,890	In Stock
1 mL x 10 mM (in DMSO)	$516	In Stock

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Batch Information

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Purity:97.88%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.
Synonyms	GW-869682X, GW869682X, GW 869682X

Chemical Properties

Molecular Weight	448.46
Formula	C₂₃H₂₈O₉
Cas No.	408504-26-7
Smiles	O(C1=C(CC2=CC=C(OC)C=C2)C=CC=C1)[C@@H]3O[C@H](COC(OCC)=O)[C@@H](O)[C@H](O)[C@H]3O
Relative Density.	1.312 g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (111.49 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2299 mL	11.1493 mL	22.2985 mL	111.4927 mL
5 mM	0.4460 mL	2.2299 mL	4.4597 mL	22.2985 mL
10 mM	0.2230 mL	1.1149 mL	2.2299 mL	11.1493 mL
20 mM	0.1115 mL	0.5575 mL	1.1149 mL	5.5746 mL
50 mM	0.0446 mL	0.2230 mL	0.4460 mL	2.2299 mL
100 mM	0.0223 mL	0.1115 mL	0.2230 mL	1.1149 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc