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Galanthamine

Name: Galanthamine
Brand: TargetMol
SKU: T4S1725
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4S1725Cas No. 357-70-0

Alias Galantamine

Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.

Galanthamine

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Purity: 99.87%

Catalog No. T4S1725Alias GalantamineCas No. 357-70-0

Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$50	In Stock	In Stock
100 mg	$70	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.87%

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
Targets&IC50	AChE:500 nM
In vivo	Galanthamine is a selective, reversible competitive acetylcholinesterase inhibitor that has been approved for the symptomatic treatment of Alzheimer's disease[1]
Synonyms	Galantamine

Chemical Properties

Molecular Weight	287.35
Formula	C₁₇H₂₁NO₃
Cas No.	357-70-0
Smiles	COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
Relative Density.	1.28 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 58.82 mg/mL (204.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4801 mL	17.4004 mL	34.8008 mL	174.0038 mL
5 mM	0.6960 mL	3.4801 mL	6.9602 mL	34.8008 mL
10 mM	0.3480 mL	1.7400 mL	3.4801 mL	17.4004 mL
20 mM	0.1740 mL	0.8700 mL	1.7400 mL	8.7002 mL
50 mM	0.0696 mL	0.3480 mL	0.6960 mL	3.4801 mL
100 mM	0.0348 mL	0.1740 mL	0.3480 mL	1.7400 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc