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Galanthamine

🥰Excellent
Catalog No. T4S1725Cas No. 357-70-0
Alias Galantamine

Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.

Galanthamine
Other Forms of Galanthamine:
Galanthamine hydrobromideT00861953-04-4
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Galanthamine

🥰Excellent
Purity: 99.87%
Catalog No. T4S1725Alias GalantamineCas No. 357-70-0
Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$50In StockIn Stock
100 mg$70In StockIn Stock
1 mL x 10 mM (in DMSO)$50In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.87%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
Targets&IC50
AChE:500 nM
In vivo
Galanthamine is a selective, reversible competitive acetylcholinesterase inhibitor that has been approved for the symptomatic treatment of Alzheimer's disease[1]
SynonymsGalantamine
Chemical Properties
Molecular Weight287.35
FormulaC17H21NO3
Cas No.357-70-0
SmilesCOc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
Relative Density.1.28 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 58.82 mg/mL (204.7 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4801 mL17.4004 mL34.8008 mL174.0038 mL
5 mM0.6960 mL3.4801 mL6.9602 mL34.8008 mL
10 mM0.3480 mL1.7400 mL3.4801 mL17.4004 mL
20 mM0.1740 mL0.8700 mL1.7400 mL8.7002 mL
50 mM0.0696 mL0.3480 mL0.6960 mL3.4801 mL
100 mM0.0348 mL0.1740 mL0.3480 mL1.7400 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitGalanthamineCholinesterase (ChE)ApoptosisAChE
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