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KB-74935

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Catalog No. T32368Cas No. 946398-78-3
Alias KB 74935

KB-74935 is an enzyme inhibitor and a mineralocorticoid receptor antagonist used to treat cholesterol, hypolipidemia, neurological disorders, and Alzheimer's disease.

KB-74935

KB-74935

🥰Excellent
Purity: 98.86%
Catalog No. T32368Alias KB 74935Cas No. 946398-78-3
KB-74935 is an enzyme inhibitor and a mineralocorticoid receptor antagonist used to treat cholesterol, hypolipidemia, neurological disorders, and Alzheimer's disease.
Pack SizePriceAvailabilityQuantity
1 mg$366In Stock
5 mg$750In Stock
10 mg$942In Stock
25 mg$1,120In Stock
50 mg$1,290In Stock
100 mg$1,500In Stock
200 mg$1,760In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:98.86%
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Product Introduction

Bioactivity
Description
KB-74935 is an enzyme inhibitor and a mineralocorticoid receptor antagonist used to treat cholesterol, hypolipidemia, neurological disorders, and Alzheimer's disease.
AliasKB 74935
Chemical Properties
Molecular Weight479.88
FormulaC19H18ClF4N3O3S
Cas No.946398-78-3
SmilesC(F)(F)(F)C1=C(C=CC(F)=C1)N2C[C@@H](C)N(S(=O)(=O)C3=C(Cl)C=C(C(N)=O)C=C3)CC2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 4.8 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0839 mL10.4193 mL20.8385 mL104.1927 mL
5 mM0.4168 mL2.0839 mL4.1677 mL20.8385 mL
10 mM0.2084 mL1.0419 mL2.0839 mL10.4193 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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