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3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 5 mg | $72 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $168 | In Stock | |
| 50 mg | $249 | In Stock | |
| 100 mg | $369 | In Stock |
| Description | 3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis. |
| In vitro | To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide . |
| Molecular Weight | 190.24 |
| Formula | C12H14O2 |
| Cas No. | 4431-01-0 |
| Smiles | CCC1(C)C2OC(=O)C3C=CCCC123 |
| Relative Density. | 1.1 g/cm3 |
| Storage | store at low temperature | Pure form: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||
| Solubility Information | DMSO: 1.9 mg/mL (9.99 mM), Sonication is recommended. (The compound is unstable in solution, please use soon.) | |||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (5.26 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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