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Anti-BAMBI Antibody (9O25)
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Catalog No. TMAY-01295
Alias BMP and activin membrane-bound inhibitor, 2610003H06Rik
Anti-BAMBI Antibody (9O25) is a Mouse antibody targeting BAMBI. Anti-BAMBI Antibody (9O25) can be used in ELISA(Det).
Anti-BAMBI Antibody (9O25)
Anti-BAMBI Antibody (9O25)
😃Good
Catalog No. TMAY-01295Alias BMP and activin membrane-bound inhibitor, 2610003H06Rik
Anti-BAMBI Antibody (9O25) is a Mouse antibody targeting BAMBI. Anti-BAMBI Antibody (9O25) can be used in ELISA(Det).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $70 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-BAMBI Antibody (9O25) is a Mouse antibody targeting BAMBI. Anti-BAMBI Antibody (9O25) can be used in ELISA(Det). |
| Alias | BMP and activin membrane-bound inhibitor, 2610003H06Rik |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9O25 |
| Reactivity | Human |
| Application | ELISA(Det) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BAMBI / NMA (rh BAMBI / NMA; TMPY-01456; NP_036474.1; Met1-Ala152). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellular domain and a short cytoplasmic region that share sequence similarities with type 1 receptors, whose members have functions in signal transduction in various developing and pathological processes. BAMBI competes with the type 1 receptor, a receptor of the transforming growth factor-beta (TGF-beta), through functioning as negative regulators of TGF-beta by limiting the signaling range of the TGF-beta family during early embryogenesis. The expression of BAMBI can be induced by accumulated beta-catenin and BMP. The expression level of BAMBI was found aberrantly elevated in most colorectal and hepatocellular carcinomas relative to the corresponding non-cancerous tissues. It suggestes that beta-catenin and TGF-beta interfere growth arrest by inducing the expression of BAMBI, and this may contribute to colorectal and hepatocellular tumorigenesis. |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human BAMBI / NMA Protein (TMPY-01456) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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