Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TargetMol | Compound Library

Cytokine Inhibitor Library

Catalog No. L3600

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling, modulate the balance between humoral and cell-based immune responses, and are heavily involved in autoimmune and inflammatory diseases. Blocking cytokine signaling pathways by biologics has shown clinical effectiveness in these diseases. Cytokines act through receptors and activate related signaling to modulate gene expression and cell functions. Cytokine receptors activate many signaling pathways: JAK-STAT, NF-kB, MAPK, PI3K, etc. A number of small molecular weight inhibitors targeting cytokine signaling have been identified as research progresses and some are approved to be marketed. Cytokines Inhibitors Library from TargetMol, containing 815 compounds targeting cytokine signaling, can be used for high throughput and high content screening for drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Resource Download
Library compound info
Excel
SDF
Contact us for more batch information

Catalog No. L3600

Cytokine Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
Inquiry & Custom

Top Publication Citing
Use of TargetMol Products

Cite scientific literature on TargetMol products

View More

Product Description Product Description

  • A unique collection of 815 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and most of them are approved to be marketed;
  • Targets cover various cytokines including IL, CSF, IFN, TNF, TGF-beta family, growth factors, chemokine family, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Sci Citations

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Library Customization | TargetMol Library Composition

EGFR
VEGFR
TNF
IL Receptor
PDGFR
FGFR
Apoptosis
Autophagy
c-Kit
CCR
TGF-beta/Smad
FLT
CXCR
IGF-1R
Src
NF-κB
Interleukin
c-Fms
c-Met/HGFR
HER
ALK
COX
Bcr-Abl
JAK
c-RET
Endogenous Metabolite
Raf
Antibacterial
HIV Protease
CDK
CSF-1R
p38 MAPK
Aurora Kinase
ERK
Akt
NO Synthase
STAT
IFNAR
Tyrosine Kinases
Caspase
JNK
PDE
PI3K
TAM Receptor
FAK
IκB/IKK
MEK
Potassium Channel
TLR
Trk receptor
5-HT Receptor
Antioxidant
Drug Metabolite
mTOR
PKC
Reactive Oxygen Species
Ferroptosis
MAPK
NOD
Parasite
PKA
PPAR
S6 Kinase
Tyrosinase
AMPK
Antibiotic
Bcl-2 Family
Calcium Channel
Chk
Cytochromes P450
Ephrin Receptor
GSK-3
HDAC
Influenza Virus
Ligand for E3 Ligase
Mitophagy
MLK
MMP
Molecular Glues
NOD-like Receptor (NLR)
NOS
Syk
Antifungal
Antiviral
Beta Amyloid
Cholinesterase (ChE)
DNA/RNA Synthesis
HCV Protease
HIF/HIF Prolyl-Hydroxylase
Immunology/Inflammation related
Mitochondrial Metabolism
P-gp
SARS-CoV
Sodium Channel
STING
Tie-2
Virus Protease
BTK
Adrenergic Receptor
Anti-infection
Casein Kinase
Chloride channel
Dehydrogenase
Discoidin Domain Receptor (DDR)
GABA Receptor
Glucocorticoid Receptor
HBV
Integrin
IRE1
LDL
MyD88
Nrf2
p53
PARP
PDK
PLK
Prostaglandin Receptor
PYK2
RIP kinase
ROS
Sirtuin
transporter
Wnt/beta-catenin
FOXO3
Adenosine Receptor
AIM2
Amylase
Annexin A
Antifection
Apelin receptor
Arrestin
CaMK
cAMP
Cell Cycle Arrest
CFTR
c-Myc
Complement System
DNA Alkylation
DNA-PK
E1/E2/E3 Enzyme
Epigenetic Reader Domain
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
FAAH
Fatty Acid Synthase
Free radical scavengers
Gap Junction Protein
Glucokinase
GluR
Glutathione Peroxidase
gp120/CD4
GPR
GTPase
Hck
HIF
Hippo pathway
Histamine Receptor
Histone Acetyltransferase
iGluR
IRAK
Leukotriene Receptor
Lipase
Lipoxygenase
LRRK2
LTR
MAO
Microtubule Associated
MRP
NADPH
NADPH-oxidase
NAMPT
PAD
PAI-1
PGE Synthase
Phosphatase
Phospholipase
PKM
Progesterone Receptor
Proteasome
PTEN
Pyroptosis
Reverse Transcriptase
ROCK
ROR
ROS Kinase
RSV
Serine Protease
Serine/threonin kinase
SGK
Topoisomerase
TRP/TRPV Channel
VDA
ADC Cytotoxin