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β-Chloro-L-alanine

Name: β-Chloro-L-alanine
Brand: TargetMol
SKU: T6987
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6987Cas No. 2731-73-9

Alias L-β-Chloroalanine, 3-Chloro-L-alanine

β-Chloro-L-alanine (L-β-Chloroalanine) is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.

β-Chloro-L-alanine

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Purity: 99.67%

Catalog No. T6987Alias L-β-Chloroalanine, 3-Chloro-L-alanineCas No. 2731-73-9

β-Chloro-L-alanine (L-β-Chloroalanine) is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$44	-	In Stock
1 g	$64	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.67%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

β-Chloro-L-alanine AI Summary

β-Chloro-L-alanine exhibits significant bioactivity as an antibacterial agent, particularly effective against Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus agalactiae, with a minimum inhibitory concentration (MIC) of 3.12 µg/mL. However, it shows limited activity against Streptococcus faecalis, Hemophilus influenzae, and other bacteria, with MIC values exceeding 100 µg/mL. Additionally, β-Chloro-L-alanine has demonstrated activity in multiple assays targeting the inhibition of histone lysine methyltransferases, interactions with methylated histone tails, and viruses, such as Marburg and Lassa, suggesting a potential impact on these diverse biological targets..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	β-Chloro-L-alanine (L-β-Chloroalanine) is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.
Synonyms	L-β-Chloroalanine, 3-Chloro-L-alanine

Chemical Properties

Molecular Weight	123.54
Formula	C₃H₆ClNO₂
Cas No.	2731-73-9
Smiles	[C@@H](C(O)=O)(CCl)N
Relative Density.	1.401 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 30 mg/mL (242.84 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	8.0945 mL	40.4727 mL	80.9454 mL	404.7272 mL
5 mM	1.6189 mL	8.0945 mL	16.1891 mL	80.9454 mL
10 mM	0.8095 mL	4.0473 mL	8.0945 mL	40.4727 mL
20 mM	0.4047 mL	2.0236 mL	4.0473 mL	20.2364 mL
50 mM	0.1619 mL	0.8095 mL	1.6189 mL	8.0945 mL
100 mM	0.0809 mL	0.4047 mL	0.8095 mL	4.0473 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc