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Hydrocortisone 17-butyrate

Name: Hydrocortisone 17-butyrate
Brand: TargetMol
SKU: T0270
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0270Cas No. 13609-67-1

Alias Hydrocortisone butyrate, Cortisol 17-butyrate

Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.

Hydrocortisone 17-butyrate

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Purity: 99.57%

Catalog No. T0270Alias Hydrocortisone butyrate, Cortisol 17-butyrateCas No. 13609-67-1

Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.

Pack Size	Price	Availability
100 mg	$29	In Stock
200 mg	$38	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.57%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
Synonyms	Hydrocortisone butyrate, Cortisol 17-butyrate

Chemical Properties

Molecular Weight	432.55
Formula	C₂₅H₃₆O₆
Cas No.	13609-67-1
Smiles	CCCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C
Relative Density.	1.0914 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (288.98 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3119 mL	11.5594 mL	23.1187 mL	115.5936 mL
5 mM	0.4624 mL	2.3119 mL	4.6237 mL	23.1187 mL
10 mM	0.2312 mL	1.1559 mL	2.3119 mL	11.5594 mL
20 mM	0.1156 mL	0.5780 mL	1.1559 mL	5.7797 mL
50 mM	0.0462 mL	0.2312 mL	0.4624 mL	2.3119 mL
100 mM	0.0231 mL	0.1156 mL	0.2312 mL	1.1559 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc