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Antitumor agent-88
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Catalog No. T72552Cas No. 1422527-87-4
Antitumor agent-88, a competitive inhibitor of CYP1A1 (K i: 1.4 μM), demonstrates significant antimitotic activity by arresting cells in the G2/M phase and disrupting the microtubule network and cytoskeleton in CYP1A1-expressing breast cancer cells.
Antitumor agent-88
😃Good
Catalog No. T72552Cas No. 1422527-87-4
Antitumor agent-88, a competitive inhibitor of CYP1A1 (K i: 1.4 μM), demonstrates significant antimitotic activity by arresting cells in the G2/M phase and disrupting the microtubule network and cytoskeleton in CYP1A1-expressing breast cancer cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks | 6-8 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Antitumor agent-88, a competitive inhibitor of CYP1A1 (K i: 1.4 μM), demonstrates significant antimitotic activity by arresting cells in the G2/M phase and disrupting the microtubule network and cytoskeleton in CYP1A1-expressing breast cancer cells. |
| Targets&IC50 | CYP1A1:1.4 μM (Ki) |
| Molecular Weight | 478.56 |
| Formula | C23H30N2O7S |
| Cas No. | 1422527-87-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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