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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $113 | In Stock | |
10 mg | $188 | In Stock | |
25 mg | $395 | In Stock | |
50 mg | $688 | In Stock | |
100 mg | $957 | In Stock | |
500 mg | $1,890 | In Stock | |
1 mL x 10 mM (in DMSO) | $30 | In Stock |
Description | 116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibition of simian virus 40 (SV40) replication, inhibition of tumour antigen (TAg) endogenous ATPase activity, and TAg-mediated activation of Hsp70.116-9e can be used to study cancer drug resistance. |
In vitro | 116-9e (MAL2-11B) inhibits Hsp70 stimulated by TAg more effectively than MAL3-101, significantly reducing virus replication and DNA synthesis. MAL2-11B also inhibits the activity of the TAg ATPase domain[1].116-9e (MAL2-11B; 15 μM; 5 days) significantly decreases BK virus in human renal cell lines[2]. |
Alias | MAL-2-11B, MAL2-11B, MAL211B, MAL 2 11B, MAL2 11B |
Molecular Weight | 512.6 |
Formula | C31H32N2O5 |
Cas No. | 831217-43-7 |
Storage | |Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (156.07 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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