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116-9e

Catalog No. T25770   CAS 831217-43-7
Synonyms: MAL 2 11B, MAL2 11B, MAL211B, MAL-2-11B, MAL2-11B

MAL2-11B is a Simian Virus 40 replication inhibitor. It acts by targeting the molecular chaperone function and ATPase activity of T antigen. MAL2-11B is also a MAL3-101 precursor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
116-9e, CAS 831217-43-7
Pack Size Availability Price/USD Quantity
50 mg 6-8 weeks
$ 789.00
$ 631.00
100 mg 6-8 weeks
$ 1,280.00
$ 1,024.00
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description MAL2-11B is a Simian Virus 40 replication inhibitor. It acts by targeting the molecular chaperone function and ATPase activity of T antigen. MAL2-11B is also a MAL3-101 precursor.
Synonyms MAL 2 11B, MAL2 11B, MAL211B, MAL-2-11B, MAL2-11B
Molecular Weight 512.6
Formula C31H32N2O5
CAS No. 831217-43-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Ireland AW, Gobillot TA, Gupta T, Seguin SP, Liang M, Resnick L, Goldberg MT, Manos-Turvey A, Pipas JM, Wipf P, Brodsky JL. Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target. Bioorg Med Chem. 2014 Nov 15;22(22):6490-6502. doi: 10.1016/j.bmc.2014.09.019. PubMed PMID: 25440730; PubMed Central PMCID: PMC4293281. 2. Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL. Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen. Virus Res. 2009 Apr;141(1):71-80. doi: 10.1016/j.virusres.2008.12.018. Epub 2009 Feb 4. PubMed PMID: 19200446; PubMed Central PMCID: PMC2758074.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Keywords

116-9e 831217-43-7 MAL 2 11B MAL2 11B 116 9e MAL211B MAL-2-11B MAL2-11B 1169e inhibitor inhibit

 

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