Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

116-9e

🥰Excellent
Catalog No. T25770Cas No. 831217-43-7
Alias MAL2-11B, MAL-2-11B, MAL211B, MAL2 11B, MAL 2 11B

116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibiting simian virus 40 (SV40) replication, tumour antigen (TAg) endogenous ATPase activity, and TAg-mediated activation of Hsp70. 116-9e can be used to study cancer drug resistance.

116-9e

116-9e

🥰Excellent
Purity: 99.55%
Catalog No. T25770Alias MAL2-11B, MAL-2-11B, MAL211B, MAL2 11B, MAL 2 11BCas No. 831217-43-7
116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibiting simian virus 40 (SV40) replication, tumour antigen (TAg) endogenous ATPase activity, and TAg-mediated activation of Hsp70. 116-9e can be used to study cancer drug resistance.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$113In StockIn Stock
10 mg$188In StockIn Stock
25 mg$395In StockIn Stock
50 mg$662In StockIn Stock
100 mg$957In StockIn Stock
200 mg$1,280-In Stock
1 mL x 10 mM (in DMSO)$30In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.55%
Contact us for more batch information

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity
Description
116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibiting simian virus 40 (SV40) replication, tumour antigen (TAg) endogenous ATPase activity, and TAg-mediated activation of Hsp70. 116-9e can be used to study cancer drug resistance.
In vitro
116-9e (MAL2-11B) inhibits Hsp70 stimulated by TAg more effectively than MAL3-101, significantly reducing virus replication and DNA synthesis. MAL2-11B also inhibits the activity of the TAg ATPase domain[1].116-9e (MAL2-11B; 15 μM; 5 days) significantly decreases BK virus in human renal cell lines[2].
SynonymsMAL2-11B, MAL-2-11B, MAL211B, MAL2 11B, MAL 2 11B
Chemical Properties
Molecular Weight512.6
FormulaC31H32N2O5
Cas No.831217-43-7
SmilesC(OCC1=CC=CC=C1)(=O)C=2C(NC(=O)N(CCCCCC(O)=O)C2C)C3=CC=C(C=C3)C4=CC=CC=C4
Relative Density.1.205 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (156.07 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (6.44 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9508 mL9.7542 mL19.5084 mL97.5419 mL
5 mM0.3902 mL1.9508 mL3.9017 mL19.5084 mL
10 mM0.1951 mL0.9754 mL1.9508 mL9.7542 mL
20 mM0.0975 mL0.4877 mL0.9754 mL4.8771 mL
50 mM0.0390 mL0.1951 mL0.3902 mL1.9508 mL
100 mM0.0195 mL0.0975 mL0.1951 mL0.9754 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

VirusProteaseVirus Protease116-9e1169e116 9e
Related Tags: buy 116-9e | purchase 116-9e | 116-9e cost | order 116-9e | 116-9e chemical structure | 116-9e in vitro | 116-9e formula | 116-9e molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.