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Glycochenodeoxycholic Acid

Name: Glycochenodeoxycholic Acid
Brand: TargetMol
SKU: T4588
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4588Cas No. 640-79-9

Alias Lithocholylglycine, Glycochenodeoxycholate, Glycine chenodeoxycholate, GCDCA, Chenodeoxycholylglycine

Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.

Glycochenodeoxycholic Acid

🥰Excellent

Purity: 99.97%

Catalog No. T4588Alias Lithocholylglycine, Glycochenodeoxycholate, Glycine chenodeoxycholate, GCDCA, ChenodeoxycholylglycineCas No. 640-79-9

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$47	In Stock
25 mg	$76	In Stock
50 mg	$112	In Stock
100 mg	$165	In Stock
200 mg	$245	In Stock
500 mg	$416	In Stock
1 mL x 10 mM (in DMSO)	$52	In Stock

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Purity:99.97%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
Synonyms	Lithocholylglycine, Glycochenodeoxycholate, Glycine chenodeoxycholate, GCDCA, Chenodeoxycholylglycine

Chemical Properties

Molecular Weight	449.62
Formula	C₂₆H₄₃NO₅
Cas No.	640-79-9
Smiles	[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCC(O)=O
Relative Density.	1.162 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 142 mg/mL (315.82 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (8.9 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2241 mL	11.1205 mL	22.2410 mL	111.2050 mL
5 mM	0.4448 mL	2.2241 mL	4.4482 mL	22.2410 mL
10 mM	0.2224 mL	1.1121 mL	2.2241 mL	11.1205 mL
20 mM	0.1112 mL	0.5560 mL	1.1121 mL	5.5603 mL
50 mM	0.0445 mL	0.2224 mL	0.4448 mL	2.2241 mL
100 mM	0.0222 mL	0.1112 mL	0.2224 mL	1.1121 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc