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Formamide

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Catalog No. T4767Cas No. 75-12-7
Alias NSC 748, Methanamide, Formimidic acid, Carbamaldehyde

Formamide (NSC-748) is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been exposed to DMF and subsequent development of prostate cancer.

Formamide

Formamide

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Purity: 99.3%
Catalog No. T4767Alias NSC 748, Methanamide, Formimidic acid, CarbamaldehydeCas No. 75-12-7
Formamide (NSC-748) is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been exposed to DMF and subsequent development of prostate cancer.
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100 g$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.3%
Appearance:Liquid
Color:Transparent to Yellow
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Product Introduction

Bioactivity
Description
Formamide (NSC-748) is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been exposed to DMF and subsequent development of prostate cancer.
SynonymsNSC 748, Methanamide, Formimidic acid, Carbamaldehyde
Chemical Properties
Molecular Weight45.0406
FormulaCH3NO
Cas No.75-12-7
SmilesO=CN
Relative Density.1.13 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 255 mg/mL (5661.56 mM)
Ethanol: Soluble
H2O: 20 mg/mL (444.04 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM22.2022 mL111.0110 mL222.0219 mL1110.1095 mL
5 mM4.4404 mL22.2022 mL44.4044 mL222.0219 mL
10 mM2.2202 mL11.1011 mL22.2022 mL111.0110 mL
20 mM1.1101 mL5.5505 mL11.1011 mL55.5055 mL
50 mM0.4440 mL2.2202 mL4.4404 mL22.2022 mL
100 mM0.2220 mL1.1101 mL2.2202 mL11.1011 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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