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Ammonium Chloride

Name: Ammonium Chloride
Brand: TargetMol
SKU: T64755
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T64755Cas No. 12125-02-9

Ammonium chloride inhibits autophagy, regulates pH, can disrupt enzymes, and may hinder muscle mitochondrial function.

Ammonium Chloride

🥰Excellent

Catalog No. T64755Cas No. 12125-02-9

Ammonium chloride inhibits autophagy, regulates pH, can disrupt enzymes, and may hinder muscle mitochondrial function.

Pack Size	Price	Availability
100 mg	$30	In Stock
500 mg	$55	In Stock
1 g	$80	In Stock
5 g	$189	In Stock

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Product Introduction

Bioactivity

Description	Ammonium chloride inhibits autophagy, regulates pH, can disrupt enzymes, and may hinder muscle mitochondrial function.
In vitro	Ammonium Chloride (NH4Cl) reduces the yield of reovirus during infection of mouse L cells.[2]
In vivo	Ammonium Chloride (0.28 M in drinking water; 8-9-week-old C57B/L6 mice) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy. Ammonium Chloride effectively improved doxorubicin (DOX)-induced cardiomyocyte apoptosis and cardiac dysfunction in mice.[1]

Chemical Properties

Molecular Weight	53.49
Formula	ClH₄N
Cas No.	12125-02-9
Smiles	N.Cl

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 18.33 mg/mL (342.74 mM), Sonication is recommended.

H2O: 80 mg/mL (1495.61 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	18.6951 mL	93.4754 mL	186.9508 mL	934.7542 mL
5 mM	3.7390 mL	18.6951 mL	37.3902 mL	186.9508 mL
10 mM	1.8695 mL	9.3475 mL	18.6951 mL	93.4754 mL
20 mM	0.9348 mL	4.6738 mL	9.3475 mL	46.7377 mL
50 mM	0.3739 mL	1.8695 mL	3.7390 mL	18.6951 mL
100 mM	0.1870 mL	0.9348 mL	1.8695 mL	9.3475 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc