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Ammonium Chloride

Catalog No. T64755 CAS 12125-02-9

Ammonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis and metabolic acidosis, thereby affecting enzyme activity and influencing processes in biological systems.Ammonium chloride has potential antimicrobial activity. Ammonium Chloride has potential antimicrobial activity and prevents training-induced improvement in mitochondrial respiratory function in male rat flounder muscle.

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Ammonium Chloride, CAS 12125-02-9

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 55.00
1 g	In stock	$ 80.00

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Storage & Solubility Information

Description	Ammonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis and metabolic acidosis, thereby affecting enzyme activity and influencing processes in biological systems.Ammonium chloride has potential antimicrobial activity. Ammonium Chloride has potential antimicrobial activity and prevents training-induced improvement in mitochondrial respiratory function in male rat flounder muscle.
In vitro	Ammonium Chloride (NH4Cl) reduces the yield of reovirus during infection of mouse L cells.[2]
In vivo	Ammonium Chloride (0.28 M in drinking water; 8-9-week-old C57B/L6 mice) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy. Ammonium Chloride effectively improved doxorubicin (DOX)-induced cardiomyocyte apoptosis and cardiac dysfunction in mice.[1]

Molecular Weight	53.49
Formula	ClH4N
CAS No.	12125-02-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 38 mg/mL(710 mM)

H2O: 80 mg/mL(1.49 M)

References and Literature

1. Huang X, et al. NH4Cl treatment prevents doxorubicin-induced myocardial dysfunction in vivo. Life Sci. 2019 Jun 15;227:94-100. 2. Canning WM, et al. Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science. 1983 Feb 25;219(4587):987-8.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Inhibitor Library EMA Approved Drug Library FDA-Approved Drug Library Autophagy Compound Library Approved Drug Library Bioactive Compounds Library Max Bioactive Compound Library

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Keywords

Ammonium Chloride 12125-02-9 Autophagy Microbiology/Virology Antifungal inhibitor inhibit

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