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Ammonium chloride, for molecular biology
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Catalog No. T64755Cas No. 12125-02-9
Ammonium chloride, for molecular biology, is utilized in the study of molecular biology and serves as a zwitterionic compound to adjust pH levels. It can induce intracellular alkalization and metabolic acidosis, thereby affecting enzyme activity and influencing biological system processes. Additionally, ammonium chloride acts as an autophagy inhibitor and a lysosomal inhibitor.
Ammonium chloride, for molecular biology
🥰Excellent
Catalog No. T64755Cas No. 12125-02-9
Ammonium chloride, for molecular biology, is utilized in the study of molecular biology and serves as a zwitterionic compound to adjust pH levels. It can induce intracellular alkalization and metabolic acidosis, thereby affecting enzyme activity and influencing biological system processes. Additionally, ammonium chloride acts as an autophagy inhibitor and a lysosomal inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $30 | In Stock | |
| 500 mg | $55 | In Stock | |
| 1 g | $80 | In Stock | |
| 5 g | $189 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ammonium chloride, for molecular biology, is utilized in the study of molecular biology and serves as a zwitterionic compound to adjust pH levels. It can induce intracellular alkalization and metabolic acidosis, thereby affecting enzyme activity and influencing biological system processes. Additionally, ammonium chloride acts as an autophagy inhibitor and a lysosomal inhibitor. |
| In vitro | Ammonium Chloride (NH4Cl) reduces the yield of reovirus during infection of mouse L cells.[2] |
| In vivo | Ammonium Chloride (0.28 M in drinking water; 8-9-week-old C57B/L6 mice) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy. Ammonium Chloride effectively improved doxorubicin (DOX)-induced cardiomyocyte apoptosis and cardiac dysfunction in mice.[1] |
| Molecular Weight | 53.49 |
| Formula | ClH4N |
| Cas No. | 12125-02-9 |
| Smiles | Cl[NH4] |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 18.33 mg/mL (342.74 mM), Sonication is recommended.  H2O: 80 mg/mL (1495.61 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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