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Telomerase-IN-2

🥰Excellent
Catalog No. T13115Cas No. 1610878-54-0
Alias Telomerase inhibitor 2

Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).

Telomerase-IN-2

Telomerase-IN-2

🥰Excellent
Purity: 99.32%
Catalog No. T13115Alias Telomerase inhibitor 2Cas No. 1610878-54-0
Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$135In StockIn Stock
5 mg$336In StockIn Stock
10 mg$493In StockIn Stock
25 mg$892In StockIn Stock
50 mg$1,330-In Stock
1 mL x 10 mM (in DMSO)$469In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.32%
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Product Introduction

Bioactivity
Description
Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).
Targets&IC50
Telomerase:0.89 µM
In vitro
Telomerase-IN-2 exhibits high activity against Hela, SMMC-7721, SGC-7901, U87 and HepG2 cell lines in the anticancer activity assay in vitro[1].
SynonymsTelomerase inhibitor 2
Chemical Properties
Molecular Weight633.69
FormulaC34H39N3O9
Cas No.1610878-54-0
SmilesCOc1cc(OC)c2c(c1)oc(-c1cc(OC)c(OC)c(OC)c1)c(OCCCCN1CCN(CC1)C(=O)c1ccncc1)c2=O
Relative Density.1.32 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 235 mg/mL (370.84 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (7.89 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5781 mL7.8903 mL15.7806 mL78.9029 mL
5 mM0.3156 mL1.5781 mL3.1561 mL15.7806 mL
10 mM0.1578 mL0.7890 mL1.5781 mL7.8903 mL
20 mM0.0789 mL0.3945 mL0.7890 mL3.9451 mL
50 mM0.0316 mL0.1578 mL0.3156 mL1.5781 mL
100 mM0.0158 mL0.0789 mL0.1578 mL0.7890 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Telomerase-IN-2TelomeraseIN2Telomerase IN 2TelomeraseInhibitorinhibit
Related Tags: buy Telomerase-IN-2 | purchase Telomerase-IN-2 | Telomerase-IN-2 cost | order Telomerase-IN-2 | Telomerase-IN-2 chemical structure | Telomerase-IN-2 in vitro | Telomerase-IN-2 formula | Telomerase-IN-2 molecular weight
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