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3-O-Acetyl-16α-hydroxytrametenolic acid
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Catalog No. TN1256Cas No. 168293-13-8
Alias 3-O-Acetyl-16 alpha-hydroxytrametenolic acid
3-O-Acetyl-16α-hydroxytrametenolic acid exhibits inhibitory activities against AAPH-induced hemolysis of red blood cells and demonstrates strong inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
3-O-Acetyl-16α-hydroxytrametenolic acid
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Purity: 99.75%
Catalog No. TN1256Alias 3-O-Acetyl-16 alpha-hydroxytrametenolic acidCas No. 168293-13-8
3-O-Acetyl-16α-hydroxytrametenolic acid exhibits inhibitory activities against AAPH-induced hemolysis of red blood cells and demonstrates strong inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $89 | - | In Stock | |
| 5 mg | $263 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $448 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.75%
Appearance:Solid
Color:White
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | 3-O-Acetyl-16α-hydroxytrametenolic acid exhibits inhibitory activities against AAPH-induced hemolysis of red blood cells and demonstrates strong inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. |
| In vitro | In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells. |
| Synonyms | 3-O-Acetyl-16 alpha-hydroxytrametenolic acid |
| Molecular Weight | 514.74 |
| Formula | C32H50O5 |
| Cas No. | 168293-13-8 |
| Smiles | [H][C@@]12CCC3=C(CC[C@]4(C)[C@@H]([C@@H](CCC=C(C)C)C(O)=O)[C@H](O)C[C@@]34C)[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C |
| Relative Density. | 1.11 g/cm3 (Predicted) |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
InhibitorinhibitInflammationrelatedInflammation relatedImmunologyrelatedImmunology/Inflammation relatedImmunology relatedImmunology & Inflammation related3-O-Acetyl-16α-hydroxytrametenolic acid3OAcetyl16αhydroxytrametenolic acid3-O-Acetyl-16alpha-hydroxytrametenolic acid3-O-Acetyl-16a-hydroxytrametenolic acid3-O-Acetyl-16 α-hydroxytrametenolic acid3-O-Acetyl-16 a-hydroxytrametenolic acid3 O Acetyl 16α hydroxytrametenolic acid
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