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IMB-XMA0038

Name: IMB-XMA0038
Brand: TargetMol
SKU: T71725
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T71725Cas No. 921812-26-2

Alias IMBXMA0038

IMB-XMA0038 is a novel inhibitor targeting Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase with antimicrobial activity for use in tuberculosis research.

IMB-XMA0038

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Purity: 99.96%

Catalog No. T71725Alias IMBXMA0038Cas No. 921812-26-2

IMB-XMA0038 is a novel inhibitor targeting Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase with antimicrobial activity for use in tuberculosis research.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$293	-	In Stock
5 mg	$722	-	In Stock
10 mg	$987	-	In Stock
25 mg	$1,520	-	In Stock
50 mg	$1,980	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.96%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	IMB-XMA0038 is a novel inhibitor targeting Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase with antimicrobial activity for use in tuberculosis research.
In vitro	Synergistic effects were observed for IMB-XMA0038 when used together with almost all other anti-tuberculosis drugs against most Mtb isolates. IMB-XMA0038 exhibited greater activity than rifampin against Mtb under hypoxic conditions, as reflected by CFU decreases of 1.1-log-unit versus 0.8-log-unit, respectively, for IMB-XMA0038 and rifampin concentrations of 4 × MIC. [1]
Synonyms	IMBXMA0038

Chemical Properties

Molecular Weight	294.22
Formula	C₁₁H₁₀N₄O₆
Cas No.	921812-26-2
Smiles	O=C(C1=CC=C([N+]([O-])=O)O1)NC2=NN=C(C3OCCC3)O2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (169.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3988 mL	16.9941 mL	33.9882 mL	169.9409 mL
5 mM	0.6798 mL	3.3988 mL	6.7976 mL	33.9882 mL
10 mM	0.3399 mL	1.6994 mL	3.3988 mL	16.9941 mL
20 mM	0.1699 mL	0.8497 mL	1.6994 mL	8.4970 mL
50 mM	0.0680 mL	0.3399 mL	0.6798 mL	3.3988 mL
100 mM	0.0340 mL	0.1699 mL	0.3399 mL	1.6994 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc