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MBX-4132

Name: MBX-4132
Brand: TargetMol
SKU: T13767
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T13767Cas No. 2286411-30-9

MBX-4132, inhibit trans translation by binding to the bacterial ribosome,is a member of a chemical class called oxadiazoles.

MBX-4132

🥰Excellent

Purity: 98.31%

Catalog No. T13767Cas No. 2286411-30-9

MBX-4132, inhibit trans translation by binding to the bacterial ribosome,is a member of a chemical class called oxadiazoles.

Pack Size	Price	Availability
5 mg	$36	In Stock
10 mg	$59	In Stock
25 mg	$119	In Stock
50 mg	$197	In Stock
100 mg	$295	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:98.31%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	MBX-4132, inhibit trans translation by binding to the bacterial ribosome,is a member of a chemical class called oxadiazoles.
In vitro	MBX-4132, has several characteristics that could make it a match for Neisseria gonorrhoeae (N. gonorrhoeae).?which interferes with protein synthesis by blocking trans translation.

Chemical Properties

Molecular Weight	338.34
Formula	C₁₈H₁₅FN₄O₂
Cas No.	2286411-30-9
Smiles	Fc1ccc(cc1)-c1nnc(NC(=O)N2CCc3ccccc3C2)o1
Relative Density.	1.382 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (59.11 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9556 mL	14.7780 mL	29.5561 mL	147.7803 mL
5 mM	0.5911 mL	2.9556 mL	5.9112 mL	29.5561 mL
10 mM	0.2956 mL	1.4778 mL	2.9556 mL	14.7780 mL
20 mM	0.1478 mL	0.7389 mL	1.4778 mL	7.3890 mL
50 mM	0.0591 mL	0.2956 mL	0.5911 mL	2.9556 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc