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AQ-13 dihydrochloride

🥰Excellent
Catalog No. T10356Cas No. 169815-40-1

AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.

AQ-13 dihydrochloride

AQ-13 dihydrochloride

🥰Excellent
Purity: 99.81%
Catalog No. T10356Cas No. 169815-40-1
AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30In StockIn Stock
5 mg$68In StockIn Stock
10 mg$112In StockIn Stock
25 mg$226In StockIn Stock
50 mg$338In StockIn Stock
100 mg$483In StockIn Stock
500 mg$1,050In StockIn Stock
1 mL x 10 mM (in DMSO)$76In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.81%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.
In vivo
Slight decreases in the PCE/RBC ratio are observed in male and female rats treated with CQ, and in females treated with AQ-13 alone; however, these changes are not statistically significant.
Chemical Properties
Molecular Weight364.74
FormulaC16H24Cl3N3
Cas No.169815-40-1
SmilesCl.Cl.CCN(CC)CCCNc1ccnc2cc(Cl)ccc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (274.17 mM), Sonication is recommended.
DMSO: 70 mg/mL (191.92 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.48 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.7417 mL13.7084 mL27.4168 mL137.0840 mL
5 mM0.5483 mL2.7417 mL5.4834 mL27.4168 mL
10 mM0.2742 mL1.3708 mL2.7417 mL13.7084 mL
20 mM0.1371 mL0.6854 mL1.3708 mL6.8542 mL
50 mM0.0548 mL0.2742 mL0.5483 mL2.7417 mL
100 mM0.0274 mL0.1371 mL0.2742 mL1.3708 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ParasiteInhibitorinhibitAQ-13 DihydrochlorideAQ13 dihydrochlorideAQ13 DihydrochlorideAQ-13AQ13AQ 13 dihydrochlorideAQ 13 DihydrochlorideAQ 13
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