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AQ-13 dihydrochloride

Name: AQ-13 dihydrochloride
Brand: TargetMol
SKU: T10356
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10356Cas No. 169815-40-1

AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.

AQ-13 dihydrochloride

🥰Excellent

Purity: 99.81%

Catalog No. T10356Cas No. 169815-40-1

AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$68	In Stock	In Stock
10 mg	$112	In Stock	In Stock
25 mg	$226	In Stock	In Stock
50 mg	$338	In Stock	In Stock
100 mg	$483	In Stock	In Stock
500 mg	$1,050	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$76	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.81%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.
In vivo	Slight decreases in the PCE/RBC ratio are observed in male and female rats treated with CQ, and in females treated with AQ-13 alone; however, these changes are not statistically significant.

Chemical Properties

Molecular Weight	364.74
Formula	C₁₆H₂₄Cl₃N₃
Cas No.	169815-40-1
Smiles	Cl.Cl.CCN(CC)CCCNc1ccnc2cc(Cl)ccc12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (274.17 mM), Sonication is recommended.

DMSO: 70 mg/mL (191.92 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.48 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.7417 mL	13.7084 mL	27.4168 mL	137.0840 mL
5 mM	0.5483 mL	2.7417 mL	5.4834 mL	27.4168 mL
10 mM	0.2742 mL	1.3708 mL	2.7417 mL	13.7084 mL
20 mM	0.1371 mL	0.6854 mL	1.3708 mL	6.8542 mL
50 mM	0.0548 mL	0.2742 mL	0.5483 mL	2.7417 mL
100 mM	0.0274 mL	0.1371 mL	0.2742 mL	1.3708 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc