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HT-2157

Name: HT-2157
Brand: TargetMol
SKU: T5455
Price: 51 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5455Cas No. 303149-14-6

Alias SNAP-37889, SNAP37889

HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.

HT-2157

🥰Excellent

Purity: 98.33%

Catalog No. T5455Alias SNAP-37889, SNAP37889Cas No. 303149-14-6

HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.

Pack Size	Price	Availability
5 mg	$51	In Stock
10 mg	$89	In Stock
25 mg	$173	In Stock
50 mg	$317	In Stock
100 mg	$533	In Stock
1 mL x 10 mM (in DMSO)	$57	In Stock

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Batch Information

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Purity:98.33%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
Synonyms	SNAP-37889, SNAP37889

Chemical Properties

Molecular Weight	366.34
Formula	C₂₁H₁₃F₃N₂O
Cas No.	303149-14-6
Smiles	O=C1N(C=2C(C1=NC3=CC(C(F)(F)F)=CC=C3)=CC=CC2)C4=CC=CC=C4
Relative Density.	1.29 g/cm3 (Predicted)
Color	Orange
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (122.84 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7297 mL	13.6485 mL	27.2970 mL	136.4852 mL
5 mM	0.5459 mL	2.7297 mL	5.4594 mL	27.2970 mL
10 mM	0.2730 mL	1.3649 mL	2.7297 mL	13.6485 mL
20 mM	0.1365 mL	0.6824 mL	1.3649 mL	6.8243 mL
50 mM	0.0546 mL	0.2730 mL	0.5459 mL	2.7297 mL
100 mM	0.0273 mL	0.1365 mL	0.2730 mL	1.3649 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc