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HS220

Name: HS220
Brand: TargetMol
SKU: T60011
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60011Cas No. 1570374-32-1

HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.

HS220

🥰Excellent

Purity: 99.39%

Catalog No. T60011Cas No. 1570374-32-1

HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.

Pack Size	Price	Availability
1 mg	$45	In Stock
5 mg	$112	In Stock
10 mg	$178	In Stock
25 mg	$295	In Stock
50 mg	$392	In Stock
100 mg	$536	In Stock
200 mg	$736	In Stock
1 mL x 10 mM (in DMSO)	$118	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.39%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.

Chemical Properties

Molecular Weight	323.35
Formula	C₁₈H₁₇N₃O₃
Cas No.	1570374-32-1
Smiles	CCCn1c(NC(=O)c2cccc(c2)C(O)=O)nc2ccccc12
Relative Density.	1.30 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (139.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0926 mL	15.4631 mL	30.9262 mL	154.6312 mL
5 mM	0.6185 mL	3.0926 mL	6.1852 mL	30.9262 mL
10 mM	0.3093 mL	1.5463 mL	3.0926 mL	15.4631 mL
20 mM	0.1546 mL	0.7732 mL	1.5463 mL	7.7316 mL
50 mM	0.0619 mL	0.3093 mL	0.6185 mL	3.0926 mL
100 mM	0.0309 mL	0.1546 mL	0.3093 mL	1.5463 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc