Shopping Cart

Your shopping cart is currently empty

FAUC-365

Name: FAUC-365
Brand: TargetMol
SKU: T21667
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T21667Cas No. 474432-66-1

FAUC-365 is a D3 dopamine receptor agonist.

FAUC-365

😃Good

Purity: 99.62%

Catalog No. T21667Cas No. 474432-66-1

FAUC-365 is a D3 dopamine receptor agonist.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$113	In Stock	In Stock
10 mg	$172	In Stock	In Stock
25 mg	$339	In Stock	In Stock
50 mg	$538	In Stock	In Stock
100 mg	$778	In Stock	In Stock
500 mg	$1,620	-	In Stock
1 mL x 10 mM (in DMSO)	$125	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.62%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	FAUC-365 is a D3 dopamine receptor agonist.
Targets&IC50	5-HT:0.50 nM(Ki)
In vitro	As a dichloro derivative, FAUC-365 revealed D3 affinities that were comparable to its methoxy-substituted analogs, however, the selectivities of FAUC-365 against 5HT-1A, 5-HT2, and R1 were substantially higher, which was demonstrated by the extraordinary selectivity ratios of 17600, 7200, 5200, and 680 over D1, D2long, D2short, and D4, respectively, were determined for FAUC-365 with Ki of 0.50 nM. In addition, the benzothiophene analog FAUC 346 and its oxa analog showed partial agonist character with EC50 values at 0.36 and 1.5 nM, respectively [1].

Chemical Properties

Molecular Weight	462.44
Formula	C₂₃H₂₅Cl₂N₃OS
Cas No.	474432-66-1
Smiles	Clc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4s3)CC2)c1Cl
Relative Density.	1.300 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: insoluble

DMSO: 50 mg/mL (108.12 mM), Sonication is recommended.

EtOH: insoluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1624 mL	10.8122 mL	21.6244 mL	108.1221 mL
5 mM	0.4325 mL	2.1624 mL	4.3249 mL	21.6244 mL
10 mM	0.2162 mL	1.0812 mL	2.1624 mL	10.8122 mL
20 mM	0.1081 mL	0.5406 mL	1.0812 mL	5.4061 mL
50 mM	0.0432 mL	0.2162 mL	0.4325 mL	2.1624 mL
100 mM	0.0216 mL	0.1081 mL	0.2162 mL	1.0812 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc