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Lenacil

Name: Lenacil
Brand: TargetMol
SKU: T20092
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20092Cas No. 2164-08-1

Alias Herbicide, 634 Hexilure

Lenacil (634 Hexilure) is an agent of herbicide.Lenacil can inhibit photosynthesis.

Lenacil

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Purity: 99.65%

Catalog No. T20092Alias Herbicide, 634 HexilureCas No. 2164-08-1

Lenacil (634 Hexilure) is an agent of herbicide.Lenacil can inhibit photosynthesis.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$30	In Stock	In Stock
25 mg	$52	In Stock	In Stock
50 mg	$84	In Stock	In Stock
100 mg	$137	In Stock	In Stock
200 mg	$196	-	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.65%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Lenacil AI Summary

Lenacil exhibits a range of bioactivities across various assays. It demonstrates significant inhibitory effects on photosynthetic electron transport at photosystem II, with an IC50 of 79.98 nM in Spinacia oleracea chloroplasts, and shows differential inhibitory potency in s-triazine-susceptible (IC50: 1000.0 nM) and -resistant (IC50: 20000.0 nM) Poa annua leaf thylakoid membranes. Additionally, it functions as an activator of the Thyroid Stimulating Hormone Receptor with a potency of 39810.7 nM and increases intracellular cAMP concentrations in HEK 293 cells. Lenacil also exhibits inhibitory effects on Chronic Active B-Cell Receptor Signaling (potency: 7307.8 nM) and acts as an agonist of the Etiologic Mutation responsible for Fibrous Dysplasia/McCune-Albright Syndrome (potency: 2818.4 nM). Furthermore, it shows potency in inhibiting human tyrosyl-DNA phosphodiesterase 1 in the presence of CPT with a potency of 11582.1 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Lenacil (634 Hexilure) is an agent of herbicide.Lenacil can inhibit photosynthesis.
Synonyms	Herbicide, 634 Hexilure

Chemical Properties

Molecular Weight	234.29
Formula	C₁₃H₁₈N₂O₂
Cas No.	2164-08-1
Smiles	O=C1NC2=C(CCC2)C(=O)N1C1CCCCC1
Relative Density.	1.32

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 18.33 mg/mL (78.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2682 mL	21.3411 mL	42.6821 mL	213.4107 mL
5 mM	0.8536 mL	4.2682 mL	8.5364 mL	42.6821 mL
10 mM	0.4268 mL	2.1341 mL	4.2682 mL	21.3411 mL
20 mM	0.2134 mL	1.0671 mL	2.1341 mL	10.6705 mL
50 mM	0.0854 mL	0.4268 mL	0.8536 mL	4.2682 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc