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(R)-baclofen

🥰Excellent
Catalog No. T6355Cas No. 69308-37-8
Alias STX209, Arbaclofen

(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.

(R)-baclofen

(R)-baclofen

🥰Excellent
Purity: 98.94%
Catalog No. T6355Alias STX209, ArbaclofenCas No. 69308-37-8
(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$32In StockIn Stock
10 mg$53In StockIn Stock
25 mg$112In Stock-
50 mg$189In Stock-
100 mg$293In Stock-
200 mg$417In Stock-
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.94%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.
In vitro
Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. [1] Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(?)-enantiomer is about 100 times more active than the S-(+)-enantiomer.
SynonymsSTX209, Arbaclofen
Chemical Properties
Molecular Weight213.66
FormulaC10H12ClNO2
Cas No.69308-37-8
SmilesNC[C@H](CC(O)=O)c1ccc(Cl)cc1
Relative Density.1.285 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10 mM, Sonication is recommended.
DMSO: Insoluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM4.6803 mL23.4017 mL46.8033 mL234.0167 mL
5 mM0.9361 mL4.6803 mL9.3607 mL46.8033 mL
10 mM0.4680 mL2.3402 mL4.6803 mL23.4017 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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