Shopping Cart
Remove All
Your shopping cart is currently empty
Angoline hydrochloride
🥰Excellent
Catalog No. T75672Cas No. 1071676-04-4
Alias 6-Methoxyldihydrochelerythrine
Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling.
Angoline hydrochloride
🥰Excellent
Purity: 98.6%
Catalog No. T75672Alias 6-MethoxyldihydrochelerythrineCas No. 1071676-04-4
Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $40 | - | In Stock | |
| 2 mg | $59 | - | In Stock | |
| 5 mg | $97 | - | In Stock | |
| 10 mg | $142 | - | In Stock | |
| 25 mg | $263 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.6%
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
| Description | Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling. |
| Targets&IC50 | STAT3:11.56 μM |
| In vitro | Angoline hydrochloride acting in the range of 0 to 100 μM for 1 hr was able to inhibit STAT3, STAT1 and NF-κB signaling pathways with the IC50 of 11.56 μM, >100 μM and >100 μM, respectively. Angoline hydrochloride acted in the range of 0 to 100 μM for 2 hours and was able to affect the phosphorylation process of STAT3. Angoline hydrochloride acting in the range of 0 to 100 μM for 72 hours was able to inhibit the proliferation of MDA-MB-231, H4 and HepG2 cells. [1] |
| Synonyms | 6-Methoxyldihydrochelerythrine |
| Molecular Weight | 415.87 |
| Formula | C22H22ClNO5 |
| Cas No. | 1071676-04-4 |
| Smiles | Cl.O(C=1C=CC=2C3=CC=C4C=C5OCOC5=CC4=C3N(C)C(OC)C2C1OC)C |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Angoline hydrochloride | purchase Angoline hydrochloride | Angoline hydrochloride cost | order Angoline hydrochloride | Angoline hydrochloride chemical structure | Angoline hydrochloride in vitro | Angoline hydrochloride formula | Angoline hydrochloride molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.