Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
2 mg | In stock | $ 58.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 163.00 | |
25 mg | In stock | $ 322.00 | |
50 mg | In stock | $ 497.00 | |
100 mg | In stock | $ 747.00 | |
200 mg | In stock | $ 987.00 | |
500 mg | In stock | $ 1,520.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 119.00 |
Description | VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively. |
In vitro | VU0483605 shows excellent mGlu1 PAM activity at both human and rat (pEC50 = 6.45 ± 0.11, 113 ± 5% Glu Max) and no activity as an mGlu4 PAM (EC50 >10 μM)[1]. |
Molecular Weight | 446.67 |
Formula | C20H10Cl3N3O3 |
CAS No. | 1623101-11-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (212.68 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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