Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK4/6-IN-5 is a highly effective inhibitor of CDK4 and CDK6, with Ki values of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively (WO2019207463A1, example A93).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 970.00 |
Description | CDK4/6-IN-5 is a highly effective inhibitor of CDK4 and CDK6, with Ki values of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively (WO2019207463A1, example A93). |
In vitro | The CDK4/6 inhibitor, CDK4/6-IN-5, exhibits cell-based IC50 values of 23.8 nM and 61.4 nM against JEKO-1 and MV4-11 cells, respectively, targeting CDK4 and CDK6[1]. |
Synonyms | CDK4/6-IN-5 |
Molecular Weight | 527.01 |
Formula | C22H28ClFN6O4S |
CAS No. | 2380321-50-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CDK4/6-IN-5 2380321-50-4 CDK4/6IN5 CDK4/6 IN 5 CDK-4/6-IN-5 inhibitor inhibit