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DW71177

Name: DW71177
Brand: TargetMol
SKU: T85333
Price: 81 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T85333Cas No. 2241311-72-6

Alias DW-71177, DW 71177

DW71177 is a bd1-selective and potent BET inhibitor with potent anti-leukemic activity for the study of leukemia.

DW71177

🥰Excellent

Purity: 98.13%

Catalog No. T85333Alias DW-71177, DW 71177Cas No. 2241311-72-6

DW71177 is a bd1-selective and potent BET inhibitor with potent anti-leukemic activity for the study of leukemia.

Pack Size	Price	Availability
1 mg	$81	In Stock
5 mg	$198	In Stock
10 mg	$318	In Stock
25 mg	$639	In Stock
50 mg	$987	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.13%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	DW71177 is a bd1-selective and potent BET inhibitor with potent anti-leukemic activity for the study of leukemia.
Synonyms	DW-71177, DW 71177

Chemical Properties

Molecular Weight	384.48
Formula	C₂₀H₂₈N₆O₂
Cas No.	2241311-72-6
Smiles	O=C(NCCCCNC1=NC=2C=C(OC)C=CC2N3C1=NN=C3C)CC(C)C
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (104.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6009 mL	13.0046 mL	26.0092 mL	130.0458 mL
5 mM	0.5202 mL	2.6009 mL	5.2018 mL	26.0092 mL
10 mM	0.2601 mL	1.3005 mL	2.6009 mL	13.0046 mL
20 mM	0.1300 mL	0.6502 mL	1.3005 mL	6.5023 mL
50 mM	0.0520 mL	0.2601 mL	0.5202 mL	2.6009 mL
100 mM	0.0260 mL	0.1300 mL	0.2601 mL	1.3005 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc