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Lovastatin hydroxy acid sodium

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Catalog No. T19918Cas No. 75225-50-2
Alias Mevinolinic acid sodium, Mevinolin sodium, 6-α-Methylcompactin sodium

Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.6 nM, which can lower cholesterol.

Lovastatin hydroxy acid sodium

Lovastatin hydroxy acid sodium

😃Good
Purity: 99.92%
Catalog No. T19918Alias Mevinolinic acid sodium, Mevinolin sodium, 6-α-Methylcompactin sodiumCas No. 75225-50-2
Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.6 nM, which can lower cholesterol.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$85-In Stock
5 mg$198-In Stock
10 mg$318-In Stock
25 mg$623-In Stock
50 mg$887-In Stock
100 mg$1,190-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.92%
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Product Introduction

Bioactivity
Description
Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.6 nM, which can lower cholesterol.
Targets&IC50
HMG-CoA reductase:0.6 nM (Ki)
SynonymsMevinolinic acid sodium, Mevinolin sodium, 6-α-Methylcompactin sodium
Chemical Properties
Molecular Weight444.54
FormulaC24H37NaO6
Cas No.75225-50-2
Smiles[O-]C(C[C@H](O)C[C@H](O)CC[C@@H]1[C@@]2([H])[C@H](C[C@H](C=C2C=C[C@@H]1C)C)OC([C@@H](C)CC)=O)=O.[Na+]
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10.00 mg/mL (22.50 mM), Sonication is recommended.
H2O: 10.00 mg/mL (22.50 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.2495 mL11.2476 mL22.4952 mL112.4758 mL
5 mM0.4499 mL2.2495 mL4.4990 mL22.4952 mL
10 mM0.2250 mL1.1248 mL2.2495 mL11.2476 mL
20 mM0.1125 mL0.5624 mL1.1248 mL5.6238 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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