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Dihydromethysticin

Name: Dihydromethysticin
Brand: TargetMol
SKU: TQ0191
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TQ0191Cas No. 19902-91-1

Alias (+)-Dihydromethysticin

Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23.

Dihydromethysticin

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Purity: 99.85%

Catalog No. TQ0191Alias (+)-DihydromethysticinCas No. 19902-91-1

Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$64	In Stock	In Stock
5 mg	$152	In Stock	In Stock
10 mg	$228	In Stock	In Stock
25 mg	$347	In Stock	In Stock
50 mg	$496	-	In Stock
100 mg	$693	-	In Stock
1 mL x 10 mM (in DMSO)	$170	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.85%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23.
Synonyms	(+)-Dihydromethysticin

Chemical Properties

Molecular Weight	276.28
Formula	C₁₅H₁₆O₅
Cas No.	19902-91-1
Smiles	COC1=CC(=O)O[C@@H](CCc2ccc3OCOc3c2)C1
Relative Density.	1.28 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (108.59 mM), Sonication is recommended.

Ethanol: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.24 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6195 mL	18.0976 mL	36.1952 mL	180.9758 mL
5 mM	0.7239 mL	3.6195 mL	7.2390 mL	36.1952 mL
10 mM	0.3620 mL	1.8098 mL	3.6195 mL	18.0976 mL
20 mM	0.1810 mL	0.9049 mL	1.8098 mL	9.0488 mL
50 mM	0.0724 mL	0.3620 mL	0.7239 mL	3.6195 mL
100 mM	0.0362 mL	0.1810 mL	0.3620 mL	1.8098 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc