Bisdionin C

Name: Bisdionin C
Brand: TargetMol
SKU: T40863
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40863Cas No. 74857-22-0

Bisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).

Bisdionin C

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Purity: 98.67%

Catalog No. T40863Cas No. 74857-22-0

Pack Size	Price	Availability
1 mg	$34	In Stock
2 mg	$48	In Stock
5 mg	$83	In Stock
10 mg	$131	In Stock
25 mg	$238	In Stock
50 mg	$358	In Stock
100 mg	$521	In Stock
200 mg	$718	In Stock

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Purity:98.67%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Bisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).
Targets&IC50	Chitinase B1:0.2 μM(A. fumigatus), Chitotriosidase (human macrophage):8.3 μM, AMCase:3.4 μM

Chemical Properties

Molecular Weight	400.39
Formula	C₁₇H₂₀N₈O₄
Cas No.	74857-22-0
Smiles	Cn1cnc2n(C)c(=O)n(CCCn3c(=O)n(C)c4ncn(C)c4c3=O)c(=O)c12
Relative Density.	1.58 g/cm3 (Predicted)

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Slightly soluble

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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